[Official Home Page of the Otezla® (apremilast) Healthcare Professional Site | Amgen Inc. Learn about Otezla® (apremilast), a treatment for adults with moderate to severe plaque psoriasis, active psoriatic arthritis, or oral ulcers associated with Behçet's disease. Review the mechanism of action (MOA), the clinical trial program, efficacy data, and safety information. Access educational materials for your patients and information about prescribing and starting patients on Otezla. Please see full Important Safety Information.]