[Explore IDH: Why Patients with AML, Glioma, or Cholangiocarcinoma Should Be Tested for IDH Mutations Many patients with acute myeloid leukemia (AML), glioma, or cholangiocarcinoma have an isocitrate dehydrogenase (IDH) mutation. Learn about IDH mutations and cancer. Agios is committed to transforming lives of patients living with cancer.]